EPA vs DHA: they are not the same omega-3
- Peer reviewed
- GRADE evidence
- Independent
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Quick answer
EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are both omega-3 fatty acids but serve different roles. EPA is primarily an inflammation modulator. DHA is a structural component of cell membranes, especially in the brain and retina. The ratio of EPA to DHA in a supplement should match the intended use.
Common ratios
- General wellness: 1.5 to 2 EPA per 1 DHA (typical fish oil)
- Brain or eye support: 1 EPA per 1.5 to 2 DHA
- Inflammation focus: 3 to 4 EPA per 1 DHA
Dosing
Typical adult dose: 1000 to 2000 mg combined EPA plus DHA per day, with food.
Citations
- PMID 22356735 (EPA vs DHA review)
- PMID 23320913 (Omega-3 and cardiovascular biomarkers)
FAQ
- Fish oil vs algae oil?
- Is more EPA always better?
- Should I take omega-3 with vitamin E?